sismid
Short course on Pathogen evolution, selection and immunity
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trvrb/sismid
Immunity and immune-mediated competition
Slides
Pathogen comparison
Exercise: Review main immune interactions for chosen pathogens
Question: What are the main immune selective pressures on the pathogen?
Additional resources
Issue of the
Philosophical Transactions of the Royal Society
,
Within-host dynamics of infection: from ecological insights to evolutionary predictions
Cobey, S. 2014.
Pathogen evolution and the immunological niche.
Annals of the NY Academy of Sciences
1320:1-15.
Lipsitch and O’Hagan. 2007.
Patterns of antigenic diversity and the mechanisms that maintain them.
J. R. Soc. Interface
4(16):787-802.